Prof. Dr. Kerstin Kaufmann

Profil

Zusammenfassung

Kerstin Kaufmann erforscht die molekulare Kontrolle der Pflanzenentwicklung, insbesondere wie Transkriptionsfaktoren die Blütenbildung und Organspezifikation steuern. Sie kombiniert Genomik, Chromatin-Analyse und Genregulation, um zu verstehen, wie sich Entwicklungsprogramme durch DNA-Bindung und Genexpression dynamisch verändern. Ihre Expertise ist relevant für die Biotechnologie, um Pflanzeneigenschaften gezielt zu verändern oder Entwicklungsprozesse besser zu kontrollieren.

Skills

Name

Prof. Dr. Kerstin Kaufmann

Titel

Prof. Dr.

Fakultät

Lebenswissenschaftliche Fakultät

Institut

Institut für Biologie

Arbeitsgruppe

Pflanzliche Zell- und Molekularbiologie

E-Mail

🔒 nur für eingeloggte sichtbarAnmelden

Telefon

🔒 nur für eingeloggte sichtbarAnmelden

HU-FIS-Profil

Quelle ↗

Zuletzt gescrapt

28.6.2026, 01:07:34

• Analyse von Organidentitaeten in Blueten auf der Ebene einzelner Zellen

  Quelle ↗

  Förderer: DFG Sachbeihilfe Zeitraum: 07/2020 - 06/2024 Projektleitung: Prof. Dr. Kerstin Kaufmann

• Bildgebungssystem in Nanometerskala für lebende Zellen auf Basis der Fluoreszenzlebensdauer

  Quelle ↗

  Zeitraum: 05/2026 - 05/2028 Projektleitung: Prof. Dr. Marina Mikhaylova, Prof. Dr. Kerstin Kaufmann, Prof. Andrew Plested

• Einsteinprofessur Kerstin Kaufmann

  Quelle ↗

  Förderer: Einstein Professur Zeitraum: 12/2025 - 12/2027 Projektleitung: Prof. Dr. Kerstin Kaufmann

🔒 Das System hat 220 mögliche Industrie-Partner gefunden — Firmen, Scores und Begründungen sind nur für eingeloggte Nutzer:innen sichtbar. Anmelden

• <i>JUNGBRUNNEN1</i> , a Reactive Oxygen Species–Responsive NAC Transcription Factor, Regulates Longevity in <i>Arabidopsis</i>

  2012

  The Plant Cell · 607 Zitationen · DOI

  The transition from juvenility through maturation to senescence is a complex process that involves the regulation of longevity. Here, we identify JUNGBRUNNEN1 (JUB1), a hydrogen peroxide (H(2)O(2))-induced NAC transcription factor, as a central longevity regulator in Arabidopsis thaliana. JUB1 overexpression strongly delays senescence, dampens intracellular H(2)O(2) levels, and enhances tolerance to various abiotic stresses, whereas in jub1-1 knockdown plants, precocious senescence and lowered abiotic stress tolerance are observed. A JUB1 binding site containing a RRYGCCGT core sequence is present in the promoter of DREB2A, which plays an important role in abiotic stress responses. JUB1 transactivates DREB2A expression in mesophyll cell protoplasts and transgenic plants and binds directly to the DREB2A promoter. Transcriptome profiling of JUB1 overexpressors revealed elevated expression of several reactive oxygen species-responsive genes, including heat shock protein and glutathione S-transferase genes, whose expression is further induced by H(2)O(2) treatment. Metabolite profiling identified elevated Pro and trehalose levels in JUB1 overexpressors, in accordance with their enhanced abiotic stress tolerance. We suggest that JUB1 constitutes a central regulator of a finely tuned control system that modulates cellular H(2)O(2) level and primes the plants for upcoming stress through a gene regulatory network that involves DREB2A.

• MIKC-type MADS-domain proteins: structural modularity, protein interactions and network evolution in land plants

  2005

  Gene · 600 Zitationen · DOI

• Orchestration of Floral Initiation by APETALA1

  2010

  Science · 520 Zitationen · DOI

  The MADS-domain transcription factor APETALA1 (AP1) is a key regulator of Arabidopsis flower development. To understand the molecular mechanisms underlying AP1 function, we identified its target genes during floral initiation using a combination of gene expression profiling and genome-wide binding studies. Many of its targets encode transcriptional regulators, including known floral repressors. The latter genes are down-regulated by AP1, suggesting that it initiates floral development by abrogating the inhibitory effects of these genes. Although AP1 acts predominantly as a transcriptional repressor during the earliest stages of flower development, at more advanced stages it also activates regulatory genes required for floral organ formation, indicating a dynamic mode of action. Our results further imply that AP1 orchestrates floral initiation by integrating growth, patterning, and hormonal pathways.

• Charité – Universitätsmedizin Berlin

  IGRK 2403/1: Analyse und Umbau des regulatorischen Genoms

  university

• Duke University

  IGRK 2403/1: Analyse und Umbau des regulatorischen Genoms

  university

• Ludwig-Maximilians-Universität München

  SFB/TRR 175/3: Mechanismen und Komponenten der GUN1/GLK Signalleitung und ihre Bedeutung für die Akklimatisation (TP C05)

  university