Die Forschung von Prof. Dr. Sebastian Markett konzentriert sich auf die Integration von Neurowissenschaften, Genetik und Kognition, um biologische Alterungsprozesse und psychische Gesundheit zu verstehen. Durch den Einsatz multimodaler Bildgebungsverfahren wie fMRI und maschineller Lernverfahren werden Konnektome und kognitive Funktionen analysiert. Ein weiterer Schwerpunkt liegt auf der Untersuchung von Persönlichkeitsmerkmalen wie Neurotizismus und deren Zusammenhang mit digitalen Verhaltensmustern. Die Arbeiten stützen sich stark auf Längsschnittstudien und die Integration großer Datensätze aus Genomik und Neuroimaging.
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Prof. Dr. Sebastian Markett
HU-FIS-Profil ↗Förderer: DFG Sachbeihilfe Zeitraum: 05/2018 - 07/2024 Projektleitung: Prof. Dr. Sebastian Markett
Förderer: DFG Sachbeihilfe Zeitraum: 01/2026 - 12/2028 Projektleitung: Prof. Dr. Sebastian Markett
Asia-Pacific Psychiatry · DOI
INTRODUCTION: It has been hypothesized that two distinctive forms of Internet addiction exist. Here, generalized Internet addiction refers to the problematic use of the Internet covering a broad range of Internet-related activities. In contrast, specific forms of Internet addiction target the problematic use of distinct online activities such as excessive online video gaming or activities in social networks. METHODS: The present study investigates the relationship between generalized and specific Internet addiction in a cross-cultural study encompassing data from China, Taiwan, Sweden and Germany in n = 636 participants. In this study, we assessed - besides generalized Internet addiction - addictive behavior in the domains of online video gaming, online shopping, online social networks and online pornography. RESULTS: The results confirm the existence of distinct forms of specific Internet addiction. One exception, however, was established in five of the six samples under investigation: online social network addiction correlates in large amounts with generalized Internet addiction. DISCUSSION: In general, it is of importance to distinguish between generalized and specific Internet addiction.
Human Brain Mapping · DOI
In the recent past, various intrinsic connectivity networks (ICN) have been identified in the resting brain. It has been hypothesized that the fronto-parietal ICN is involved in attentional processes. Evidence for this claim stems from task-related activation studies that show a joint activation of the implicated brain regions during tasks that require sustained attention. In this study, we used functional magnetic resonance imaging (fMRI) to demonstrate that functional connectivity within the fronto-parietal network at rest directly relates to attention. We applied graph theory to functional connectivity data from multiple regions of interest and tested for associations with behavioral measures of attention as provided by the attentional network test (ANT), which we acquired in a separate session outside the MRI environment. We found robust statistical associations with centrality measures of global and local connectivity of nodes within the network with the alerting and executive control subfunctions of attention. The results provide further evidence for the functional significance of ICN and the hypothesized role of the fronto-parietal attention network.
Behavioural Brain Research · DOI